Identification of senescent cell surface targetable protein DPP4
نویسندگان
چکیده
منابع مشابه
Identification of senescent cell surface targetable protein DPP4.
Senescent cell accumulation in aging tissues is linked to age-associated diseases and declining function, prompting efforts to eliminate them. Mass spectrometry analysis revealed that DPP4 (dipeptidyl peptidase 4) was selectively expressed on the surface of senescent, but not proliferating, human diploid fibroblasts. Importantly, the differential presence of DPP4 allowed flow cytometry-mediated...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2017
ISSN: 0890-9369,1549-5477
DOI: 10.1101/gad.302570.117